Evaluation of zinc sulfate effect in prevention ofchemotherapy-induced mucositis in Patients with cancer referred to Emam Ali Hospital in 2008-2009
Phase 3
- Conditions
- Chemotherapy-induced mucositis.Other and unspecified lesions of oral mucosa
- Registration Number
- IRCT201101023133N3
- Lead Sponsor
- Zahedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
chemotherapy treatment with a regimen that had the same mucositis probability, Karnovsky performance status case equal or more than 60, life expectancy equal to or more than 6 months, White Blood Cell count equal to or more than 1500 and platelet count equal to or more than 100000/µL
Exclusion criteria: radiotherapy in the head and neck region, including nasopharynx, oropharynx, and larynx previously or simultaneously, previous head and neck surgery due to malignancy, use of dentures, pregnancy, infection
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mucositis. Timepoint: Two weeks after initiation of chemotherapy and every two weeks until. Method of measurement: The patients are examined under a headlight, using dental explorers and mirrors. Data were recorded. Oral mucositis patients were labelled from 0 to 4 ,using World Health.
- Secondary Outcome Measures
Name Time Method Pain. Timepoint: Two weeks after initiation of chemotherapy and every two weeks untilthe end of chemotherapy phase. Method of measurement: The patients are examined under a headlight, using dental explorers and mirrors. Data were recorded. Oral mucositis patients were labelled from 0 to 4 ,using World Health.;Xerostomia. Timepoint: Two weeks after initiation of chemotherapy and every two weeks untilthe end of chemotherapy phase. Method of measurement: The patients are examined under a headlight, using dental explorers and mirrors. Data were recorded.;Quality of life. Timepoint: Two weeks after initiation of chemotherapy and every two weeks untilthe end of chemotherapy phase. Method of measurement: Quality of life a questionnaire(EORTC LQ-OES18) is filled out each meeting individually by the dental student.