JPRN-jRCTs031210263招募中1 期
Safety and efficacy of imatinib therapy administered in patients with Pulmonary Tumor Thrombotic Microangiopathy (PTTM) : A prospective study
Hatano Masaru0 个研究点目标入组 20 人开始时间: 2021年8月20日最近更新:
适应症
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1)Pulmonary hypertension (mean pulmonary artery pressure over 25 mmHg by right heart catheterization or RVSP over 40 mmHg by echocardiography)
- •2)cancer (diagnosed or suspected)
- •3)sign of right heart failure
- •4)hypoxemia
- •5)age over 20 year-old
- •6)sex both
- •7)Written informed consent
- •8)available as out-patient after discharge
排除标准
- •1)severe liver dysfunction, renal dysfunction or cardiovascular disease (not due to right heart failure)
- •2)taking Lomitapide within 7 days
- •3)Total bilirubin > 2.0 x reference value at registration
- •4)ALT, AST > 4.0 x reference value at registration
- •5)HBV carrier
- •6)taking Imatinib due to not PTTM
- •7)allergy or severe side effect to Imatinib
- •8)Pregnant, unwilling to practice contraception during the study
- •9)lactating female
- •10)participating other clinical trial within 4 months
- •11)judged to be inappropriate by physician (in/outpatient)
研究者
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