IRCT201302261030N12
Completed
Phase 2
Efficacy of Imatinib Mesylate in the treatment of refractory cutaneous chronic Graft Versus-Host Disease
Hematology-Oncology and SCT Research Center0 sites28 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- cutaneous cGVHD.
- Sponsor
- Hematology-Oncology and SCT Research Center
- Enrollment
- 28
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inclusion Criteria
- •1\- The patient shall undergo allogen bone marrow transplantation and have clinical and pathological cutaneous CGVHD criteria.
- •2\- Patient’s cutaneous signs are not improved by taking corticosteroids with doses of 0\.5 mg/kg at least for 3 months and cyclosporine.
- •3\- The cutaneous signs shall be active.
- •4\- The patient shall be aged between 16 to 60 years old.
- •Exclusion Criteria
- •1\- Pregnancy
- •2\- Having a history of taking Rituximab.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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