Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study

Not Applicable

Active, not recruiting

• Conditions: Obsessive-Compulsive Disorder
• Interventions: Behavioral: OCD-NET

• Registration Number: NCT06470893
• Lead Sponsor: University of Miami

Brief Summary

The overarching goal of this protocol is to investigate mechanisms that influence symptom outcomes of exposure and response prevention (ERP) therapy for OCD. Mechanisms may include affective processes, learning factors, cognitive factors, or other constructs that could influence treatment outcomes. The study team will conduct this research within the context of an effective online treatment for OCD called OCD-NET. OCD-NET is bibliotherapy with coaching and its content is reflective of standard care for OCD.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-06-17
• Study First Submitted QC: 2024-06-17
• Study First Posted: 2024-06-24
• Study Start: 2024-09-23
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-25
• Last Update Posted: 2025-03-30
• Primary Completion: 2025-09-01
• Study Completion: 2025-09-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• English-speaking
• Located within the United States
• 18-90 years old
• Able to provide consent
• Current diagnosis of OCD as assessed by clinical interview

Exclusion Criteria

• Adults unable to consent

• Individuals who are not yet adults (infants, children, teenagers)

• Participants currently located outside of the United States

• Prisoners

• Participants with hoarding as the primary OCD symptom

• Severe mental illness (e.g. schizophrenia, substance abuse); organic brain syndrome; or serious, current suicidal/homicidal ideation (based on phone screening or initial assessment)

• Concurrent enrollment in another psychotherapy treatment

• Participants taking psychotropic medication may be excluded if:

  • They have started a brand new psychotropic medication within the last 12 weeks
  • They have changed the dose of their psychotropic medication within the last 4 weeks
  • They anticipate that they cannot maintain the current dose of their psychotropic medication for the duration of the study

• Participants may be excluded if they have any cognitive or physical impairments that would interfere with their participation (e.g., significant head injury, cognitive disability, dementia).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
OCD-NET Group	OCD-NET	Participants will receive the OCD-NET intervention for up to 12 months.

Primary Outcome Measures

Name	Time	Method
Change in OCD Symptoms Measured by Yale-Brown Obsessive Compulsive Scale-Second Edition (YBOCS-II)	Baseline, up to 12 months (end of treatment)	YBOCS-II scores range from 0-50, and higher scores indicate more severe illness

Trial Locations

Locations (1)

University of Miami; 🇺🇸 Miami, Florida, United States