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The McLean Hospital Corporation

πŸ‡ΊπŸ‡ΈUnited States
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Effectiveness of HabitWorks and Symptom Tracking for Anxiety and Depression

Not Applicable
Completed
Conditions
Anxiety
Depression, Anxiety
First Posted Date
2025-06-17
Last Posted Date
2025-06-17
Lead Sponsor
Mclean Hospital
Target Recruit Count
340
Registration Number
NCT07025486
Locations
πŸ‡ΊπŸ‡Έ

McLean Hospital, BElmont, Massachusetts, United States

Pharmacologic Augmentation of TMS for Depression with D-serine

Phase 1
Not yet recruiting
Conditions
Depression
First Posted Date
2025-03-14
Last Posted Date
2025-03-14
Lead Sponsor
Mclean Hospital
Target Recruit Count
60
Registration Number
NCT06876129

Stress Dynamics and Familial Risk for Depression in Female Adolescents

Not Applicable
Not yet recruiting
Conditions
Major Depressive Disorder
First Posted Date
2025-02-10
Last Posted Date
2025-05-06
Lead Sponsor
Mclean Hospital
Target Recruit Count
148
Registration Number
NCT06816329

Investigating the Protective Impact of LY-2940094 on Stress-induced Depression- and Anxiety-related Phenotypes in Humans

Phase 2
Not yet recruiting
Conditions
Depression - Major Depressive Disorder
Anxiety
Stress
Interventions
Drug: Nociceptin Receptor Antagonist (LY-2940094)
Device: DS8R Biphasic Constant Current Stimulator
First Posted Date
2025-01-22
Last Posted Date
2025-05-07
Lead Sponsor
Mclean Hospital
Target Recruit Count
50
Registration Number
NCT06786637

Open Label Extension Study of NCT06221852

Not Applicable
Conditions
Bipolar I Disorder
Schizoaffective Disorder
Psychosis
Interventions
Other: Ketogenic diet
First Posted Date
2024-08-16
Last Posted Date
2025-04-17
Lead Sponsor
Mclean Hospital
Target Recruit Count
50
Registration Number
NCT06558201
Locations
πŸ‡ΊπŸ‡Έ

McLean Hospital, Belmont, Massachusetts, United States

Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis

Phase 2
Recruiting
Conditions
Endometriosis
Interventions
Drug: Placebo
First Posted Date
2024-06-27
Last Posted Date
2025-03-18
Lead Sponsor
Mclean Hospital
Target Recruit Count
30
Registration Number
NCT06477406
Locations
πŸ‡ΊπŸ‡Έ

McLean Hospital, Belmont, Massachusetts, United States

Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder

Not Applicable
Recruiting
Conditions
Schizoaffective Disorder
Psychosis
Bipolar I Disorder
Interventions
Other: Ketogenic diet
Other: Dietary Guidelines for Americans
First Posted Date
2024-01-24
Last Posted Date
2024-08-16
Lead Sponsor
Mclean Hospital
Target Recruit Count
50
Registration Number
NCT06221852
Locations
πŸ‡ΊπŸ‡Έ

McLean Hospital, Belmont, Massachusetts, United States

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

Phase 2
Recruiting
Conditions
Schizophrenia and Related Disorders
Cognitive Impairment
Mitochondrial Alteration
Interventions
Drug: Placebo
First Posted Date
2024-01-05
Last Posted Date
2025-05-20
Lead Sponsor
Mclean Hospital
Target Recruit Count
100
Registration Number
NCT06191965
Locations
πŸ‡ΊπŸ‡Έ

Yale School of Medicine, New Haven, Connecticut, United States

πŸ‡ΊπŸ‡Έ

McLean Hospital, Belmont, Massachusetts, United States

πŸ‡¨πŸ‡­

University of Lausanne, Lausanne, Switzerland

Mechanisms of Exposure Therapy for OCD

Not Applicable
Recruiting
Conditions
Obsessive-Compulsive Disorder
Interventions
Behavioral: Exposure therapy
First Posted Date
2023-12-18
Last Posted Date
2024-11-01
Lead Sponsor
Mclean Hospital
Target Recruit Count
400
Registration Number
NCT06173752
Locations
πŸ‡ΊπŸ‡Έ

Center for Understanding and Treating Anxiety, San Diego, California, United States

πŸ‡ΊπŸ‡Έ

McLean OCDI, Belmont, Massachusetts, United States

Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale

Completed
Conditions
Stress, Psychological
Stress, Emotional
Interventions
Behavioral: Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge
Behavioral: Standardized Maths and Verbal Questions such as the ones used in SATs
Behavioral: Chronology of Perceived Discrimination Scale (CPDS)
Behavioral: International Personality Item Pool (IPIP-NEO)
First Posted Date
2023-11-30
Last Posted Date
2024-03-13
Lead Sponsor
Mclean Hospital
Target Recruit Count
500
Registration Number
NCT06152549
Locations
πŸ‡ΊπŸ‡Έ

McLean Hospital through ProlificTM, Belmont, Massachusetts, United States

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