Racial Differences in Yoga-Induced Responses

Not Applicable

Withdrawn

• Conditions: Cardiovascular and Immune Responses to Yoga

• Registration Number: NCT05598073
• Lead Sponsor: Texas State University

Brief Summary

The purpose of this study is to 1) determine whether racial differences are evident in resting arterial stiffness and ambulatory blood pressure between African Americans and Caucasians 2) compare heart rate, blood pressure and cytokine production responses to exercise (yoga) between African Americans and Caucasians; 3) compare isokinetic muscular strength between racial groups; and 4) determine if correlations exist between these measures.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-01
• Study First Submitted: 2020-01-08
• Study Start: 2020-01-15
• Primary Completion: 2020-06-01
• Study Completion: 2020-07-01
• Study First Submitted QC: 2022-10-25
• Last Update Submitted: 2022-10-25
• Study First Posted: 2022-10-28
• Last Update Posted: 2022-10-28

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Men between the ages of 18 and 39 (25 African American and 25 Caucasian) that are not professional or collegiate athletes
• Must exercise at least 3 days per week and have no more than 1 month of yoga practice.

Exclusion Criteria

• Having stage 2 hypertension (>130 mmHg for systolic / >90 mmHg for diastolic) or higher or having taken BP medications within the 3 months prior to testing
• Infection within the previous 4 weeks
• Known renal disease
• Prior myocardial infarction
• Known coronary artery disease
• Personal history of stroke
• Heart failure
• Cardiac arrhythmias
• Chronic obstructive pulmonary disease
• Recent chest pain or dyspnea
• Orthopedic limitations that preclude the execution of yoga postures
• Current insulin dependence
• Chronic inflammatory conditions
• Blindness or deafness as participants will need to follow a yoga DVD in order to complete the session
• Having practiced yoga for more than 1 month
• Having parents of mixed racial backgrounds (i.e. both parents must be Caucasian or African American)
• Not being African American or Caucasian
• Being a professional or collegiate athlete
• Being insulin-dependent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Inflammatory markers	Once immediately after the 1-hour yoga session	Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha
Arterial stiffness	Once at baseline	Cardio-ankle vascular index
Isokinetic strength	Once at baseline	Isokinetic leg extension and flexion strength assessments at 60,120,210,300, and 400 degrees per second
Ambulatory blood pressure	Once at baseline	24 hours of ambulatory blood pressure monitoring

Trial Locations

Locations (1)

Stacy Hunter; 🇺🇸 San Marcos, Texas, United States