跳至主要内容
临床试验/NCT03274193
NCT03274193已完成不适用

Effects of Yoga Training on Cardiovascular Reactivity to Psychological Stress in Patients With Hypertension

Kaohsiung Medical University Chung-Ho Memorial Hospital2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2018年3月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
2
主要终点
Change in blood pressure during rest from baseline to week 13

研究概览

简要总结

The purpose of this study is to examine the effects of 12-week yoga training on blood pressure, heart rate, heart rate variability, arterial stiffness, and total peripheral resistance during rest and psychological stress in patients with hypertension. All eligible participants will be randomly assigned to either yoga (n=40) or usual care control (n=40) group. During the 1st lab visit, the experimenter will explain the purpose and procedures of the study. If the participants understand and agree to participate in this study, they will be asked to sign the informed consent. Next, participants will fill out questionnaires, including demographic information, Physical Activity Readiness Questionnaire, perceived stress scale, anxiety inventory, exercise behavior questionnaire, and quality of life scale. Participant's resting blood pressure will be measured. Participants will then be instructed to relax in a supine position for 15 minutes while ECG is recording. Next, participants will perform 5 minutes of stroop task and 5 minutes of mental arithmetic task (mental stressors). ECG and cardiac output will be monitored throughout the whole session. After the stress period, participants will be asked to relax until heart rate becomes stable and return to baseline. The participants will perform the sit-and-reach test. After completing all the baseline testing, the yoga group will begin the training program which is 60 minutes per session, 2 times per week for 12 weeks. The control group will be asked not to participate in any exercise program during the course of the study. Participants will be filling out the same questionnaires and receive measures of blood pressure, ECG, and cardiac output at week 6 and week 12. Additionally, participants will perform the stress tasks and the sit-and-reach test again at week 12.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
20 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 20-65 years of age
  • 18.5 <=BMI<=29.9
  • have hypertension (clinical diagnosis)
  • resting systolic blood pressure 120-160 mmHg, resting diastolic blood pressure lower than 110 mmHg

排除标准

  • regular exercise behaviors or current participation in yoga programs
  • have cardiovascular diseases, pulmonary diseases, diabetes
  • have musculoskeletal problems that may affect yoga pose practice (e.g., herniated intervertebral disc, spondylolithesis, ankylosing spondylitis)
  • current pregnancy or breastfeeding
  • change of hypertension medication use within 4 weeks

结局指标

主要结局

Change in blood pressure during rest from baseline to week 13

时间窗: Blood pressure during rest will be measured at baseline and week 13.

Blood pressure will be assessed with an OMRON blood pressure monitor.

次要结局

  • Change in blood pressure during psychological stress from baseline to week 13(Blood pressure during psychological stress will be measured at baseline and week 13.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验