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Clinical Trials/NCT07531550
NCT07531550
Not yet recruiting
Not Applicable

EFFECT OF CORE STABILITY EXERCISES AND KNEE, HIP FOCUSED EXERSISES ON DYNAMIC KNEE VALGUS IN PATELLOFEMORAL PAIN SYNDROME

Cairo University1 site in 1 country36 target enrollmentStarted: May 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
36
Locations
1
Primary Endpoint
Pain Intensity During Motion

Overview

Brief Summary

Study Purpose:

The purpose of this study is to investigate the effect of adding core muscle strengthening exercises to a hip- and knee-focused exercise program on pain intensity, dynamic knee valgus (DKV), and functional outcomes in female patients with patellofemoral pain syndrome (PFPS).

Research Question:

Does adding core muscle strengthening exercises to a hip- and knee-focused exercise program have an effect on pain intensity, dynamic knee valgus (DKV), and functional outcomes in female patients with PFPS?

Detailed Description

Detailed Description:

Therefore, the current study aims to investigate the effect of adding core muscle strengthening exercises to a hip- and knee-focused exercise program on pain intensity, dynamic knee valgus (DKV), and functional outcomes in female patients with patellofemoral pain syndrome (PFPS).

The findings of this study may provide a more effective rehabilitation program for female patients with PFPS, support the use of validated outcome measures in clinical practice, and improve symptom management during activities of daily living and functional recovery within a shorter period of time. This combined approach may be more efficient than the conventional hip- and knee-focused exercise program alone. Systematic assessment and monitoring of patient outcomes are recommended to guide clinical decision-making.

Study Delimitations:

This study will be delimited to:

Female patients clinically diagnosed with patellofemoral pain syndrome (PFPS). Thirty-six participants aged 19-35 years with body mass index (BMI) up to 25 kg/m².

Assessment procedures including Visual Analogue Scale (VAS) for knee pain, dynamic knee valgus (DKV) measured using Kinovea software, and the Knee Outcome Survey-Activities of Daily Living Scale (KOS-ADLS) for knee function.

Treatment procedures:

Group A (control group): hip- and knee-focused exercise program. Group B (study group): hip- and knee-focused exercise program in addition to core muscle stability exercises.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Care Provider)

Masking Description

Double-blinded study in which both participants and physiotherapists are unaware of group allocation due to the similarity of intervention protocols.

Eligibility Criteria

Ages
19 Weeks to 35 Weeks (Child)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Thirty-six female participants diagnosed and referred with patellofemoral pain syndrome (PFPS) (retropatellar knee pain lasting more than 6 weeks).
  • Age range between 19-35 years.
  • Body Mass Index (BMI) up to 25 kg/m².

Exclusion Criteria

  • History of previous surgeries of the lower limb.
  • Clinical evidence of knee joint complex disorders, including meniscus lesions, 3-patellar tendinopathy, chondral lesions, or knee osteoarthritis.
  • 4-Presence of pronated foot.

Arms & Interventions

control group hip and knee focused exercises program

Active Comparator

Open kinetic chain exercises including side-lying hip abduction, hip external rotation (clamshell), prone hip extension, short arc quadriceps, and straight leg raises

  1. Closed kinetic chain exercises including mini wall squats and terminal knee extensions
  2. Flexibility exercises targeting tight lower extremity soft tissues, including a seated hamstring stretch, standing quadriceps stretch, and standing wall stretch for the gastrocnemius

Intervention: hip and knee-focused exercise program (Behavioral)

Study group hip and knee focused exercises program in addition to core muscle training exercises

Experimental

participants who will received the same exercise program as control group, in addition to core muscle training exercises, including the front plank, side plank, and dead bug exercises

Intervention: Core Muscle Stability Exercise Program (Behavioral)

Outcomes

Primary Outcomes

Pain Intensity During Motion

Time Frame: Baseline (pre-intervention) and at 6 weeks (post-intervention)

Pain intensity during movement will be assessed using the Visual Analog Scale (VAS). The VAS is a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity.

Knee Function

Time Frame: Baseline (pre-intervention) and at 6 weeks (post-intervention)

Knee function will be assessed using the Knee Outcome Survey (KOS). The KOS score ranges from 0 to 100, where higher scores indicate better knee function.

Pain Intensity at Rest

Time Frame: Baseline (pre-intervention) and at 6 weeks (post-intervention)

Pain intensity at rest will be assessed using the Visual Analog Scale (VAS). The VAS is a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain). Higher scores indicate greater pain intensity.

Dynamic Knee Valgus (DKV)

Time Frame: Baseline (pre-intervention) and at 6 weeks (post-intervention)

Dynamic knee valgus will be assessed by measuring the knee valgus angle in degrees during functional tasks. Higher values indicate greater valgus deviation and poorer knee alignment.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Radwa Mohamed Hussien

principal investigator

Cairo University

Study Sites (1)

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