Adapted CPR (aCPR) a Bundle of Measures for Out of Hospital Cardiac Arrest (OHCA) Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 216
- 试验地点
- 1
- 主要终点
- ROSC
研究概览
简要总结
The goal of this controlled single centre RCT is to compare frequency rates concerning return of spontaneous circulation (ROSC) in prehospital cardiac arrest. Two different algorithms (control-and interventiongroup) of advanced cardiac life support will be used to treat patients. In patients over 18 years suffering from cardiac arrest. The main question aims to answer if the frequency of ROSC differs between the groups receiving either the new Advanced Life Support (ALS) algorithm, or standard treatment.
Researchers will compare the new algorithm to the standard care algorithm to see if there is a difference .
Participants will be randomized to treatment on scene. The controlgroup will receive ALS standard treatment as performed in local protocols.
The intervention group will receive a modified treatment including:
- thorax compression via mechanical device (LUCAS 3)
- head up Cardiopulmonary Resuscitation (cpr)
- use of an impendance threshold device (ITD) module
- arterial line placement
- continuous epinephrin infusion via infusion pump
- double sequence defibrillation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age> 18 years
- •time of resuscitation <21 minutes when enrollement starts
排除标准
- •obvious pregnancy
- •contraindications for the use of Lucas 3
- •time of resuscitation >21 minutes and etCO2 <15 mmHg upon arrival of the emergency physician on scene
- •Exclusion from the emergency physician from study due to futility.
研究组 & 干预措施
ALS ERC 2025
干预措施: ERC ALS 2025 (Procedure)
adapted CPR algorithm
- thorax compression via mechanical device (LUCAS 3)
- head up cpr
- use of an ITD module
- arterial line placement
- continuous epinephrin infusion via infusion pump
- double sequence defibrillation
干预措施: aCPR algorithm (Procedure)
结局指标
主要结局
ROSC
时间窗: one minute
frequency of ROSC in the study cohort
次要结局
- Time to ROSC(Periprocedural: from enrollement to ROSC or Termination of Resuscitation (TOR))
- CO2(Periprocedural: from enrollement to ROSC orTOR)
- descriptive data(Periprocedural: during study intervention)