Testosterone for Androgen Deficiency-Like Symptoms: A three phase, placebo-controlled, double-blind crossover study for males 40 years or older who believe they have androgen-like deficiency to assess whether testosterone gel treatment is superior to a placebo gel.

Department of Andrology, Concord Repatriation General Hospital0 个研究点目标入组 40 人开始时间: 2015年1月27日最近更新: 2020年1月13日

试验速览

暂无简介。

•Men aged 40 years or older
•Believed to have androgen deficiency (AD)
•Symptoms consistent with AD (according to US clinical guidelines)
•Provides written, informed consent and is willing to comply with study requirements

•Pathologically-based AD
•Major chronic illness causing serious disability or with life expectancy less then 2 years in the opinion of the investigator
•Major cardiovascular event (new or worsened angina, infarction, angioplasty, uncontrolled arrhythmia or hypertension) within the last 6 months
•Contraindication to testosterone including prostate or breast cancer.
•History of androgen or other drug abuse within last year.
•History of HIV or viral hepatitis.
•Skin disease that may interfere with transdermal drug administration.
•History of major psychiatric disease or psychological condition that may limit understanding and compliance with study requirements.
•Regular use of medications that interfere with absorption, metabolism or action of testosterone and may require dosage change during the study.
•Haematocrit over 0.50 or history of polycythaemia

发起方

Department of Andrology, Concord Repatriation General Hospital