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Clinical Trials/NCT05728294
NCT05728294
Completed
Not Applicable

Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy

Centre Hospitalier Universitaire Vaudois1 site in 1 country50 target enrollmentFebruary 1, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Centre Hospitalier Universitaire Vaudois
Enrollment
50
Locations
1
Primary Endpoint
Intravenous morphine consumption
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly. Little is known on the type of peripheral nerve block to perform so that optimal postoperative analgesia is provided with minimum impact on the motor function. This randomised controlled double-blinded trial tested the hypothesis that a femoral nerve block provides superior analgesia than a sciatic nerve block after proximal tibial osteotomy.

Registry
clinicaltrials.gov
Start Date
February 1, 2019
End Date
March 31, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Eric Albrecht

Program Director, regional anaesthesia

Centre Hospitalier Universitaire Vaudois

Eligibility Criteria

Inclusion Criteria

  • proximal tibial osteotomy

Exclusion Criteria

  • femoral or sciatic nerve deficit,
  • pre-existing peripheral neuropathy,
  • chronic pain diagnosis,
  • pregnancy,
  • identified contraindications to peripheral nerve block (e.g., local anesthetic allergy, coagulopathy, or infection at the block site).

Outcomes

Primary Outcomes

Intravenous morphine consumption

Time Frame: 24 hours after surgery

Intravenous morphine consumption (mg)

Secondary Outcomes

  • Intravenous morphine consumption(48 hours after surgery)
  • rest pain score(48 hours after surgery)
  • dynamic pain score(48 hours after surgery)
  • Rate of postoperative nausea and vomiting(48 hours after surgery)

Study Sites (1)

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