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临床试验/NCT05728294
NCT05728294已完成不适用

Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy

Centre Hospitalier Universitaire Vaudois2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2019年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
2
主要终点
Intravenous morphine consumption

研究概览

简要总结

Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly. Little is known on the type of peripheral nerve block to perform so that optimal postoperative analgesia is provided with minimum impact on the motor function. This randomised controlled double-blinded trial tested the hypothesis that a femoral nerve block provides superior analgesia than a sciatic nerve block after proximal tibial osteotomy.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • proximal tibial osteotomy

排除标准

  • femoral or sciatic nerve deficit,
  • pre-existing peripheral neuropathy,
  • chronic pain diagnosis,
  • pregnancy,
  • identified contraindications to peripheral nerve block (e.g., local anesthetic allergy, coagulopathy, or infection at the block site).

结局指标

主要结局

Intravenous morphine consumption

时间窗: 24 hours after surgery

Intravenous morphine consumption (mg)

次要结局

  • Intravenous morphine consumption(48 hours after surgery)
  • rest pain score(48 hours after surgery)
  • dynamic pain score(48 hours after surgery)
  • Rate of postoperative nausea and vomiting(48 hours after surgery)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Eric Albrecht

Program Director, regional anaesthesia

Centre Hospitalier Universitaire Vaudois

研究点 (2)

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