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Clinical Trials/NCT04314570
NCT04314570
Not yet recruiting
Not Applicable

Saphenous Nerve Block for Post-Op Pain Control After Tibial Plateau ORIF

Stanford University0 sites50 target enrollmentMay 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Tibial Plateau Fracture
Sponsor
Stanford University
Enrollment
50
Primary Endpoint
Pain Scores
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

Fractures of the tibial plateau, while very painful, typically do not receive nerve blocks. This is because of a concern that the numbness from a nerve block would "mask" the typically painful symptoms of compartment syndrome, a condition that can lead to a permanent loss of function of the injured limb. Our study aims to evaluate the effectiveness of saphenous nerve block for pain management after surgical repair of a tibial plateau fracture. Based on cadaver studies and our clinical experience, we suspect that the saphenous nerve contributes to pain sensations of the tibial plateau and will not mask the pain from a compartment syndrome. In summary, while saphenous nerve block represents a safe option after tibial plateau open reduction internal fixation (ORIF), we aim to evaluate its effectiveness in this patient population.

Registry
clinicaltrials.gov
Start Date
May 2025
End Date
May 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jean-Louis Horn

Principal Investigator

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Tibial plateau fracture presenting for ORIF
  • Age greater than or equal to 18 years

Exclusion Criteria

  • Other concomitant life-threatening injuries
  • History of chronic pain prior to tibial plateau ORIF
  • Age \<18 years old
  • Pregnancy
  • Any condition impairing patient's ability to consent to participation in study
  • Existing condition contraindicating a nerve block
  • Non-English Speaking

Outcomes

Primary Outcomes

Pain Scores

Time Frame: Through hospital stay, an average of 3 days

Pain scores on a scale from 0 to 10 will be collected by the research staff for 1 hour following the post-operative block. Pain scores will also be collected by the nurses throughout the patient's stay.

Opioid requirements

Time Frame: Through hospital stay, an average of 3 days

Opioid medications recorded in opioid morphine equivalents will be recorded by the research staff for the first hour following the post-operative nerve block. Opioid medications will be collected by the nurses throughout the patient's stay.

Length of Stay

Time Frame: Through hospital stay, an average of 3 days

The patient's length of stay in the hospital will be collected by the research staff following the patient's discharge.

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