Passive Leg Raise Induced Stroke Volume Changes in Elderly Prior to Elective Surgery Measured by LiDCOplusTM to Guide Fluid Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Assess passive leg raise responsiveness in spontaneously breathing aged patients.
研究概览
简要总结
This is a pilot study to investigate whether patients at advanced age are fluid responders via a reversible fluid challenge, the passive leg raise test. This will be measured with a non-invasive cardiac output monitor, the LiDCO (LiDCO Hemodynamic monitoring) .
详细描述
The intervention is as simple as a passive leg raise with measurement of effect on Stroke volume.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 80 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients ≥80 years of age, undergoing elective urologic surgical procedure
排除标准
- •age <80 years, severe aortic insufficiency, first case of the day on the operation program, unavailability of research personnel and contraindication to Lithium.
研究组 & 干预措施
Passive Leg Raise (PLR)
The patient is placed in a 45 degree recumbent position. Stroke volume is measured in ml.
Intervention:The patient is placed horizontal and the legs are passively raised to 45 degrees.
Measurement:The effect of the PLR on Stroke Volume is measured. Thereafter the patient is repositioned to the initial position and Stroke Volume is measured again.
干预措施: Passive leg raise (Other)
结局指标
主要结局
Assess passive leg raise responsiveness in spontaneously breathing aged patients.
时间窗: Within 1 minute of the intervention
Stroke volume changes in ml and as per cent change compared to baseline
次要结局
- Investigate whether there is an association between a positive response to passive leg raise on stroke volume and post spinal anesthesia.(30 minutes)
研究者
Sigridur Kalman
Professor
Karolinska Institutet