NCT02977390已完成不适用
Passive Leg Raise Induced Stroke Volume Changes in Elderly Prior to Elective Surgery Measured by LiDCOplusTM to Guide Fluid Therapy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Assess passive leg raise responsiveness in spontaneously breathing aged patients.
研究概览
简要总结
This is a pilot study to investigate whether patients at advanced age are fluid responders via a reversible fluid challenge, the passive leg raise test. This will be measured with a non-invasive cardiac output monitor, the LiDCO (LiDCO Hemodynamic monitoring) .
详细描述
The intervention is as simple as a passive leg raise with measurement of effect on Stroke volume.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 80 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients ≥80 years of age, undergoing elective urologic surgical procedure
排除标准
- •age <80 years, severe aortic insufficiency, first case of the day on the operation program, unavailability of research personnel and contraindication to Lithium.
结局指标
主要结局
Assess passive leg raise responsiveness in spontaneously breathing aged patients.
时间窗: Within 1 minute of the intervention
Stroke volume changes in ml and as per cent change compared to baseline
次要结局
- Investigate whether there is an association between a positive response to passive leg raise on stroke volume and post spinal anesthesia.(30 minutes)
研究者
Sigridur Kalman
Professor
Karolinska Institutet
研究点 (2)
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