Difference in Serum Creatinine Levels In Cervical Cancer Treated Patients With Concurrent Chemoradiation in Songklanagarind Hospital: Intravenous Vs Oral Post-hydratio

Phase 1

Completed

• Conditions: Patients with cervical cancer stage II to III without obstructive uropathy underwent CCRT; Cervical cancer; CCRT; Oral post hydration; Intravenous post hydration

• Registration Number: TCTR20160107001
• Lead Sponsor: Department of Obstetrics and Gynecology Faculty of Medicine Prince of Songkla University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-07
• Study Completion: 2016-08-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

1. Cervical cancer patients with proven cell type of squamous cell carcinoma or adenocarcinoma stage II or III (FIGO) without obstructive uropathy underwent concurrent-chemoradiation therapy
2. Eastern Cooperative Oncology Group (ECOG) Performance Status 0-2

Exclusion Criteria

1.Serum creatinine level prior treatment > 1.2 mg/dl
2.Unstable vital signs
3.Known medical issues: Cardiac diseases, Liver diseases, Renal diseases
4.History of allergy to cisplatin
5.Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean difference in serum creatinine pre and post treatment with cisplatin during CCRT oral vs IV - Serum creatinine level pre and post each course of cisplatin during CCRT

Secondary Outcome Measures

Name	Time	Method
one None None