To compare the levels of Creatinine and Alkaline Phosphatase in blood in patients suffering from Chronic gum disease with and without Type 2 Diabetes Mellitus Before and After Scaling and Root Planing.
- Conditions
- Health Condition 1: K051- Chronic gingivitisHealth Condition 2: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2024/07/070634
- Lead Sponsor
- Dr Shruti Meshram
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Group A: Periodontally healthy patients with no clinical gingival inflammation and GI equal to 0, probing depth (PPD) less than or equal to 3 mm, and no radiographic evidence of bone loss
Group B: Chronic periodontitis patients without T2DM with GI greater than 1, PPD greater than or equal to 6mm and CAL greater than or equal to 5mm.
Group C: Chronic periodontitis patients with T2DM patients, GI greater than 1, PPD greater than or equal to 6mm and CAL greater than 5mm. HbA1c levels between 5-7%.
1. Patients who have undergone any periodontal therapy in the past 6 months.
2. Patients with symptoms of acute illness.
3. Patients who are on immunosuppressive therapy or having any other systemic illness.
4 Systemic anti-inflammatory treatment within the previous 3 months or regular use of specific drugs known to affect periodontal tissues.
5. Pregnant women and lactating mothers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BIOCHEMICAL PARAMETERS <br/ ><br> 1) Fasting plasma glucose (FPG) <br/ ><br>2) Post Prandial plasma glucose (PPG) <br/ ><br>3) HbA1c <br/ ><br>4) Creatinine <br/ ><br>5) Alkaline phosphatase <br/ ><br>CLINICAL PARAMETERS <br/ ><br>1.Plaque Index (P.I.) (Tureskey-Gilmore-Glickman Modification of Quigley Hein) <br/ ><br> <br/ ><br>2.Gingival Index (G.I.) (Loe and Silness, 1963) <br/ ><br> <br/ ><br>3.Probing Pocket Depth (PPD) <br/ ><br> <br/ ><br>4.Clinical Attachment Level (CAL) <br/ ><br> <br/ ><br>Timepoint: At baseline and after 4 weeks
- Secondary Outcome Measures
Name Time Method serum Alkaline phosphatase and serum creatinine levels in normal people and in people suffering from type 2 diabetes mellitusTimepoint: serum Alkaline phosphatase and serum creatinine levels before scaling and root planing and 4 weeks post scaling and root planing