NCT05151796Unknown不适用
Effect of Continuation of Aspirin Before Isolated Heart Valve Surgery on Postoperative Bleeding and Transfusion: a Single-center Retrospective Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- The number of units of packed red blood cells transfused anytime during the hospital stay
研究概览
简要总结
Whether or not continuing aspirin up to de day before surgery increases the risk of bleeding and/or prevents thrombo-embolic complications remains debated. The investigators retrospectively investigated the whether continuing aspirine within 5 days of isolated heart valve surgery increased the risk of bleeding.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Isolated heart valve surgery
排除标准
- •Antiplatelet agent other than aspirin or anticoagulant not discontinued preoperatively
- •Emergent or salvage surgery
- •Surgery for endocarditis
- •Use of NSAIDs within 48 hours before surgery
研究组 & 干预措施
Aspirin continued within 5 days before surgery
干预措施: Aspirin (Drug)
结局指标
主要结局
The number of units of packed red blood cells transfused anytime during the hospital stay
时间窗: 30 days
次要结局
- Transfusion of any type of blood product(30 days)
- Chest tube drainage(24 hours)
- Any thrombo-embolic complication(30 days)
- Surgical revision for bleeding(24 hours)
研究者
Jean François Brichant
Professor of Anesthesia
University of Liege
研究点 (1)
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