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临床试验/NCT00405613
NCT00405613已完成2 期

Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

Wake Forest University Health Sciences2 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2003年5月1日最近更新:
适应症
相关药物

试验速览

阶段
2 期
状态
已完成
入组人数
36
试验地点
2
主要终点
Oral bleeding time

研究概览

简要总结

The purpose of this study is to determine if aspirin is associated with bleeding complications following a single tooth extraction

详细描述

Aspirin is a common chronically administered preventive treatment for cardiovascular disease, but is often discontinued prior to invasive dental procedures because of concern of bleeding complications. As the goal of aspirin is often to prevent MI and stroke, the risk of these CVD outcomes with discontinuation of aspirin must be weighed against the perceived adverse event of bleeding during or following an invasive dental procedure with continuation of aspirin. The current study is a randomized controlled trial evaluating bleeding complications of aspirin vs. placebo in healthy patients schedule for a single tooth extraction.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Require a simple tooth extraction

排除标准

  • Use of previous aspirin or NSAID

结局指标

主要结局

Oral bleeding time

次要结局

  • Report of bleeding at phone follow-up at 3-7 (first follow-up) and 40-55 hours (second follow-up)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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