Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- Oral bleeding time
研究概览
简要总结
The purpose of this study is to determine if aspirin is associated with bleeding complications following a single tooth extraction
详细描述
Aspirin is a common chronically administered preventive treatment for cardiovascular disease, but is often discontinued prior to invasive dental procedures because of concern of bleeding complications. As the goal of aspirin is often to prevent MI and stroke, the risk of these CVD outcomes with discontinuation of aspirin must be weighed against the perceived adverse event of bleeding during or following an invasive dental procedure with continuation of aspirin. The current study is a randomized controlled trial evaluating bleeding complications of aspirin vs. placebo in healthy patients schedule for a single tooth extraction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Require a simple tooth extraction
排除标准
- •Use of previous aspirin or NSAID
结局指标
主要结局
Oral bleeding time
次要结局
- Report of bleeding at phone follow-up at 3-7 (first follow-up) and 40-55 hours (second follow-up)
