An Observational Study to evaluate Abdominal Wall Muscle Thickness in Living Donor Liver Transplant Recipients with Liver Cirrhosis
Not Applicable
Recruiting
- Conditions
- Health Condition 1: K740- Hepatic fibrosis
- Registration Number
- CTRI/2024/03/064780
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients with cirrhosis above 18 years of age undergoing living donor liver transplant at Institute of Liver and Biliary Sciences, New Delhi.
Exclusion Criteria
1. Patients undergoing simultaneous liver and kidney transplant.
2. Patients undergoing re-transplantation.
3. Refusal of consent.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between abdominal muscle thickness using ultrasound in living donor liver transplant recipients with End Stage Liver Disease and healthy donorsTimepoint: Preoperatively
- Secondary Outcome Measures
Name Time Method Abdominal muscle thickness using ultrasound in living donor liver transplant donorTimepoint: Preoperatively;Correlation of abdominal muscle thickness in recipient with CTP scoreTimepoint: Preoperatively;Correlation of abdominal muscle thickness in recipient with duration of ICU stayTimepoint: Postoperative follow up for 30 days;Correlation of abdominal muscle thickness in recipient with duration of mechanical ventilation and postoperative pulmonary complicationsTimepoint: Postoperative follow up for 30 days;Correlation of abdominal muscle thickness in recipient with MELD Na score <br/ ><br>Timepoint: Preoperatively;Correlation of abdominal muscle thickness in recipient with postoperative 30 day mortalityTimepoint: Postoperative follow up for 30 days;Correlation of abdominal muscle thickness in recipient with sarcopenia as measured by hand grip strength and L3 SMI on CTTimepoint: Preoperatively
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link hepatic fibrosis (K740) to abdominal wall muscle atrophy in ESLD patients post-liver transplant?
How does abdominal wall muscle thickness correlate with post-transplant survival rates in ESLD recipients compared to standard care metrics?
Which biomarkers predict response to living donor liver transplantation in ESLD patients with varying abdominal wall muscle thickness?
What adverse events are associated with abdominal wall muscle thinning in ESLD patients after liver transplantation and how are they managed?
Are there combination therapies with nutritional support that improve abdominal wall muscle thickness in ESLD patients post-transplant?