The study of the effectiveness of Gokshursiddha ghrit in vatabhippana shushka garbha with special reference to assymetrical IUGR INTRAUTERINE GROWTH RESTRICTION

Life starts from the conception.

Intra uterine life has developmental origin of health and  many disease.

The commonest problem fetus  in intrauterine life is unable to reach its growth potential, if the estimated fetal weight is less than 10th percentile of the expected weight, which is called as Intrauterine growth restriction (IUGR).

Intrauterine growth restriction not only affectes physical growth  of the fetus but  a mental and cognitive function is also affected.

Intrauterine growth restriction is a common public health problem. 10-15% pregnancies are affected  worldwide.out of total IUGRcases 70-80% caese are of assymetrical IUGR.

50% perinatal deaths are due to IUGR.

After prematurity it is the second leading cause of perinatal morbidity and mortality.

Prenatal mortality rate is  4-8 times higher in  IUGR fetuses.

In garbhani her ahar rasa is devided into three parts  for

1 Garbhposhan

2 Stanyavruddhi

3 Matru poshan .

Vata dosha plays very important role in garbhposhan, due to mithya ahar,vihar vata dosha gets vitiated causes vatabhipanna shushka garbha.

To treat this Shushka garbha  one has to do brihan chikitsa .

We can corelate vatabhipanna shushka garbh with  asymmetrical IUGR (Intrauterine growth restriction).

David Barker had discovered the relation between the lower birth weight and the higher prevalence of ischemic heart disease mortality

“Barker’s hypothesis” emerged almost 25 years ago from epidemiological studies of birth and death records that revealed a high geographic correlation between rates of infant mortality and certain classes of later adult deaths as well as an association between birthweight and rates of adult death from ischemic heart disease. These observations led to a theory that undernutrition during gestation was an important early origin of adult cardiac and metabolic disorders due to fetal programming that permanently shaped the body’s structure, function, and metabolism and contributed to adult disease. This theory stimulated interest in the fetal origins of adult disorders, which expanded and coalesced ~5 years ago with the formation of an international society for developmental origins of health and disease (DOHaD)

IUGR happens because the fetus doesn’t get enough nutrients and nourishment. This can happen if there is a problem with: the placenta, the tissue that brings nutrients and oxygen to the developing baby the blood flow in the umbilical cord, which connects the baby to the placenta

Intrauterine growth restriction also can happen if a pregnant woman:

smokes, drinks alcohol, or uses drugs

has an infection, such as cytomegalovirus, German measles (rubella), toxoplasmosis, or syphilis

takes some types of medicines, such as some seizure treatments

has a medical condition such as lupus, anemia, or clotting problems

has high blood pressure (hypertension)

is carrying a baby that has a genetic disorder or birth defect

is pregnant with multiples

Complications of  IUGR

problems with breathing and feeding

trouble keeping a steady body temperature

abnormal blood cell counts

low blood sugar level (hypoglycemia)

problems fighting off infections

RATIONAL OF STUDY

Every month there are 5-6 anc mothers with growth scan 28 weeks diagnosed as assymetrical IUGR.

There is still lack of awareness about own health as well as fetal health .

Untreated and undiagnosed iugr cases increases perinatal mortality,contributes many diseases in adult life.

Perinatal  mortality and morbidity is  mostly due to IUGR fetuses.

There is no any specific drug for IUGR other than l arginine.

Ayurveda stated many drugs for  garbh -garbhini brihin chikitsa .

Evidence based research is neded to apply these drugs to the population.