Effect of Shashankalekhadi Leha And Jivantyadi Lepa As Described In Ashtang Hridayam For The Management Of Ek Kustha W.S.R. To Psoriasis A Clinical Study

TITLE  EFFECT OF SHASHANKALEKHADI LEHA AND JIVANTYADI LEPA AS DESCRIBED IN ASHTANG HRIDAYAM FOR THE MANAGEMENT OF EK-KUSTHA W.S.R. TO PSORIASIS   A CLINICAL STUDY

 In Ayurveda all skin disorders are classified under Kustha, which arises from the aggravation of Tridoshas. Ek Kustha a type of Kshudra Kustha is mainly caused by the vitiation of Vata and Kapha doshas and closely resembles psoriasis   a chronic autoimmune skin disease characterized by erythematous scaly plaques on areas like the elbows knees and scalp

Samprapti Due to Nidana sevan  Tridosha become vitiated and cause shithilatain Twak Rakta Mamsaand Ambu dhatus resulting in the manifestation of Ek Kustha

Symptoms Rashes  dryness  fissures  scaling  itching redness and joint stiffness are common

Need for Research Psoriasis affects 0.44 to 2.8 of Indians, more common in males. The disease has significant psychological impacts including depression and suicidal tendencies  Conventional treatments like steroids and immunosuppressants have long-term side effects creating a need for safe and effective Ayurvedic alternatives

Study Design An openlabeled  single arm prospective clinical trial on 30 patients for 30 days with a 2 month followup

Patients aged 16 to 70 years were selected based on Ayurvedic diagnostic criteria

Exclusion Criteria Pregnancy  systemic diseases chronic cases over 5 years  psoriatic arthritis  or those unwilling to continue were excluded

Probable Mode of Action

Shashankalekhadi Leha

Contains Bakuchi Vidanga Pippali Chitraka Amalaki and Mandoor BhasmBalances Vata and Kapha dosha

Amalaki and Mandoor Bhasma reduce inflammation, act as antioxidants, and have Rasayana and Kushtaghna effects

Bakuchi’s psoralen compounds inhibit epidermal proliferation and modulate immune activity

Jivantayadi Lepa

Contains Jivanti Manjistha Daru Haridra Kampillaka Madar Tutha Sarjarasaand Madhuchista

Reduces itching redness and dryness

Possesses antiinflammatory, antibacterial  woundhealing and Kushtaghna properties

TREATMENT REGIMEN

 Drug                                               SHASHANKALEKHADI LEHA                                                       JIVANTYADI LEPA

 Form                                                          Leha                                                                                           lepa

 Dose                                                         3gm BD                                                                                     ¼ anguli

 Route of Administration                              Oral                                                                                          Local application

 Time of Administration                     Morning and evening                                                                         Morning and evening

 Treatment Course                                     30 days                                                                                              30 days

 Follow up                                                   2 months                                                                                       2 months

 Anupan                                                       Til Taila