Continuous and Discontinuous Determination of Propofol Concentration in Breathing Gas

Completed

• Conditions: General Anesthesia

• Registration Number: NCT00532402
• Lead Sponsor: University of Luebeck

Brief Summary

This study should compare the propofol concentration in breathing gas and in plasma (before and) after lung passage. Propofol concentrations in breathing gas are continuously measured by a sensor. For comparison a discontinuous method is used. Neurophysiologic parameters for determination of depth of anesthesia are compared to the continuous measured propofol concentration in breathing gas.

Study hypothesis: continuous measured propofol concentration in breathing gas correlates to propofol concentration in plasma and depth of anaesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09
• Study First Submitted: 2007-09-18
• Study First Submitted QC: 2007-09-19
• Study First Posted: 2007-09-20
• Study Completion: 2010-12
• Status Verified: 2012-10
• Last Update Submitted: 2012-10-29
• Last Update Posted: 2012-10-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Patient destined for general anesthesia

Exclusion Criteria

• Heart insufficiency NYHA IV
• Allergy to propofol

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (2)

Dept. of Anesthesiology , UK-SH, Campus Luebeck; 🇩🇪 Luebeck, Schleswig-Holstein, Germany

Dept. of Anesthesiology, UK-SH, Campus Luebeck; 🇩🇪 Luebeck, Schleswig-Holstein, Germany