Breath Gas Measurement of Propofol During Anesthesia in Patients With Endourological Procedures
Not Applicable
Completed
- Conditions
- Urological Disease
- Registration Number
- NCT01835340
- Lead Sponsor
- University of Luebeck
- Brief Summary
Propofol can be measured continuously in breath gas during anesthesia. This study compares propofol concentration in plasma and breath gas and processed electroencephalographic monitoring (bispectral index) under clinical conditions with patients and total intravenous anesthesia. Target controlled infusion technique is used to deliver adequate propofol concentration in plasma.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
• 18 years of age
- Written informed consent
- Ability and willingness to give written informed consent
- American Society of Anesthesiologists (ASA) risk score I-II
Exclusion Criteria
- Denial of the patient
- Patients ASA physical status III- IV
- Pregnancy
- Volunteers with history of neurological disease or stroke
- Volunteers with a history of recreational drug abuse
- Volunteers with a history of alcohol abuse
- Known drug allergies
- History of adverse events during general anesthesia
- Total intravenous anesthesia not practicable
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Exhaled propofol (parts per billion) Continuous measurement over 40 min during the induction of anesthesia and 30 min during recovery of anesthesia
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Dept. of Anesthesiology and Intensive Care
🇩🇪Luebeck, Schleswig-Holstein, Germany