Evaluation of chitosan as a pulpotomy agent in primary molars- an in vivo study
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- This study aims to clinically and radiographically evaluate the success of Chitosan as a medicament for pulpotomy.
研究概览
简要总结
The literature cites Chitosan’s hemostaticcapability by functioning as a scaffold for clot formation and providing astrong primary closure at the wound site. Chitosan is said to haveanti-inflammatory properties help in tissue regeneration and the hemostaticactivity is attributed to its positively charged amino functional group causingan electrostatic interaction with the negatively charged blood cell leading toclot formation which in turn offers an antibacterial barrier.
Therefore, the goal of this study is toassess the effectiveness of Chitosan as a pulpotomy medicament both clinicallyand radiographically and if successful recommend its use for pulpotomyprocedures in the future.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 4.00 Year(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Large carious lesion in an otherwise restorable primary tooth 2.No spontaneous pain.
- •3.More than two-thirds of the root length is still present 4.No sign of internal or external root resorption 5.Hemorrhage from the amputated pulp site is controlled within 5 minutes.
排除标准
- •1.Not fulfilling the above-mentioned clinical or radiographic criteria.
- •2.Inability to achieve hemostasis within 5 minutes of pressure application with a moist cotton pellet.
- •3.Bright red bleeding at the amputated pulp site.
结局指标
主要结局
This study aims to clinically and radiographically evaluate the success of Chitosan as a medicament for pulpotomy.
时间窗: 6 months
次要结局
- Chitosan can be used as an alternative to formocresol for pulpotomy procedure.(6 months)