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Analgesic effect of intrathecal morphine combined with low dose local anesthetics on postoperative analgesia after liver resection: A randomized, controlled preliminary study

Not Applicable
Completed
Conditions
Diseases of the digestive system
Registration Number
KCT0003464
Lead Sponsor
Yonsei University Health System, Severance Hospital
Brief Summary

Intrathecal morphine does provide additional analgesic benefits but morphine with bupivcaine may induce further unwanted side effects and must be cautioned against.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
91
Inclusion Criteria

1. Age over 19 years
2. Patients receiving liver resection under general anesthesia (Including open surgery and laparoscopic surgery)
3. American Society of Anesthesiologists (ASA) physical status 1,2

Exclusion Criteria

1. Patients presenting with coagulopathy prior to surgery
2. Patients with neurological deficits
3. Patients with spinal anomaly or disorders
4. Patients with allergies to opioids or local anesthetics
5. Patients with severe respiratory, cardiovascular, renal, or hepatic disorders
6. Severe systemic infection or infections involving proposed intrathecal injection site
7. Patients with severe psychological disorders severe that may interfere with pain evaluation
8. Patients with chronic diseases that require opioids
9. Patients unable to read the consent form / foreigners

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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