Comparison of intrathecal morphine with bupivacaine and intravenous morphine for post-operative analgesia in laparoscopic liver resectio
Phase 1
- Conditions
- iver disease undergo laparoscopic liver surgery, comparison postoperative analgesia (morphine consumption)Liver resection, liver surgery
- Registration Number
- TCTR20211015004
- Lead Sponsor
- King Chulalongkorn Memorial hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 44
Inclusion Criteria
Patient who was scheduled for laparoscopic liver resection with specialty hepatobiliary surgeon with general anesthesia at King Chulalongkorn Memorial Hospital, and American Society of Anesthesiology Physical Status (ASA) I-III
Exclusion Criteria
1.Refuse to participate this study
2.Allergy to any drug in this study
3.Serious diseases other than liver diseases, such as cardiovascular, respiratory or endocrine system conditions
4.Contraindication for spinal anesthesia
5.Taking chronic sedatives drug and opioid - alcoholics or drug abuse
6.Psychaitic problems
7.Abody mass index (BMI) >= 30 kg/m 2
8.History of malignant hyperthermia
9.Cannot use PCA (Patient controlled analgesia)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative morphine consumption At 12 hours after intervention Morphine consumption
- Secondary Outcome Measures
Name Time Method Postoperative morphine consumption At 24,36, and 48 hours after intervention Morphine consumption,Postoperative Pain at 12, 24, 36, and 48 hour At 12,24,36, and 48 hour after intervention Numeric rating scale,Incident postoperative shoulder pain At PACU Shoulder pain (Yes/No),Patient Satisfaction At 48 postoperative Patient Satisfaction Score,Surgical bleeding End of operation Bleeding (ml)