Comparison between two drugs (bupivacaine and morphine) for relieving post operative pain after total hip replacement surgery in ankylosing spondylitis patients by administration through your lower back(caudal space)
- Conditions
- Health Condition 1: null- Patients suffering from ankylosing spondylitis undergoing total hip replacement surgery.
- Registration Number
- CTRI/2015/06/005869
- Lead Sponsor
- SUMIT BANSA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
i)Age > 18 and < 60 years.
ii)ASA grade I & II patients.
iii)Patients diagnosed to ankylosing spondylitis.
iv)Patients scheduled for total hip replacement surgery
1.ASA grade III / IV
2.History of bleeding /coagulation disorders.
3.Prolonged prothrombin time ( > 3 secs. as compared to control) or low platelet count ( < 1,00,000 / mm3 ).
4. Revision THR surgery.
5.Pregnant patients
6.Morbid obesity ( BMI >= 40 kg/m2 ).
7.History of focal neurological deficit.
8.Congenital abnormality of sacrococcygeal area.
9.History of sensory or motor disorders of limb to be operated.
10.Patients with active infection at site of caudal block.
11.History of allergy to local anaesthetics.
12. History of regular opioid use.
13. Inability to comprehend VAS assessment scale.
14. Inability to understand the use of patient controlled analgesia (PCA) device
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)To compare the efficacy of 0.125% bupivacaine alone or in combination with 50 mcg/kg of morphine administered via caudal route for relief of postoperative pain in patients of ankylosing spondylitis under going total hip replacement surgery.Timepoint: 48 hours
- Secondary Outcome Measures
Name Time Method 1)To assess the success of catheter placement by comparing the length of caudal epidural catheter threaded without resistance as compared to the length predetermined by measuring the distance from apex of sacral hiatus to L2- L3 interspaceTimepoint: 48 hours;2)To confirm radiologically, the vertebral level to which the epidural catheter has reached.Timepoint: 48 hours