NRS 2002 as a Predictor of Prognosis in COPD With Respiratory Failure

Completed

• Conditions: Pulmonary Disease, Chronic Obstructive; Respiratory Insufficiency

• Registration Number: NCT02942797
• Lead Sponsor: West China Hospital

Brief Summary

This is a prospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during April 2017 to March 2019. The following variables will be prospectively studied: age, sex, height, weight, respiratory function indicators, arterial blood gas analysis results, biochemical data, nutritional risk screening 2002 (NRS 2002) score, short-term and long-term prognostic outcomes. The purpose of this study is to assess whether NRS 2002 is a useful prognosis predictor in COPD patients with respiratory failure.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-10-11
• Study First Submitted QC: 2016-10-21
• Study First Posted: 2016-10-24
• Study Start: 2017-04-01
• Primary Completion: 2019-03-22
• Study Completion: 2019-03-22
• Status Verified: 2019-12
• Last Update Submitted: 2019-12-18
• Last Update Posted: 2019-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 520

Inclusion Criteria

• Newly diagnosis of COPD at West China Hospital during April 2017 to March 2019
• Partial pressure of O2 (PaO2) < 60 mmHg and/or partial pressure of CO2 (PaCO2) >50 mmHg
• Age ≥ 18 years
• Respiratory rates > 23 bpm

Exclusion Criteria

• Pregnancy or during lactation
• Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems
• Refused to participate in this study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of mortality	up to 2 years
Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of complications	up to 2 years
Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of length of stay	up to 2 years
Predictive value of NRS 2002 in identifying COPD patients with respiratory failure who will have poor prognostic outcomes, in terms of 30-day readmission after discharge	up to 2 years

Secondary Outcome Measures

Name	Time	Method
Collection of Demographics (age, sex)	up to 2 years

Trial Locations

Locations (1)

West China Hospital; 🇨🇳 Chengdu, Sichuan, China