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临床试验/NCT03514472
NCT03514472已完成不适用

Impact of Dried Moringa Oleifera Leaves as Value Added Supplement in Enhancing Hemoglobin Status of Reproductive Aged Females of Low Socio-economic Group

Kinnaird College for Women0 个研究点目标入组 34 人开始时间: 2013年1月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
34
主要终点
Improvement in Hemoglobin status

研究概览

简要总结

This research project is aimed at combating the nutritional deficiencies (Iron deficiency anemia) of reproductive aged females belonging to the underprivileged group of the society. Since anemia is one of the causes of still child-birth, preterm and low birth weight babies causing cognitive disabilities during the later years of life, So, it needs to be treated on priority bases.

详细描述

Mal-nutrition is a significant problem in the developing world, with serious consequences for human health and socio-economic development. It is estimated that over 43% women of reproductive age suffer from anemia. In Pakistan, about 35% non-pregnant and 51% pregnant women are suffering from anemia. Prevention and control against anemia rely on iron supplementation and food fortification on large scale. Both these methods are not affordable and feasible for poor people. Previous studies have shown that about 97% females do not meet their iron requirements. The possible reason to this can be iron losses from body including menstruation. To overcome these problems, culturally accepted, inexpensive and modified recipes were used to supply iron with addition of Moringa oleifera leaves (rich and cheap source of iron). In the study 34 of ages between 13-30 years were selected (excluding pregnant and lactating women) and were intervened with value added supplement " Moringa oleifera" for a period of three months. These recipes were made part of the diet by giving a dose of three meals per day on regular basis. Each recipe contained about 15 g of Dried Moringa powder. After the intervention, out of total 34, 3 females achieved normal Hb level of 12 g/dl. Overall, 94% cases of the study showed improvement of 1.8 g/dl (on average) in Hb level after intervention. There was a significant increase in blood Hb level (p<0.000) and both the var5iables were strongly and positively correlated (0.928). Variables of age and levels of education were weakly but significantly related to each other (p<0.001) in improving Hb after intervention.

Females with higher levels of education showed better response towards intervention.

After intervention with Moringa oleifera, an average increase of 1.5 g/dl in Hb was observed in the entire population whereas, members of Group B (ages above 18) showed more increase of 14.96% in their Hb level as compared to members of Group A (ages below 18) showing an increase of 12.96% in Hb level.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
13 Years 至 30 Years(Child, Adult)
性别
Female
接受健康志愿者

入选标准

  • Reproductive aged females (13-30 years)

排除标准

  • pregnant and Lactating women

研究组 & 干预措施

Group A (Below 18 years)

Active Comparator

Dried Moringa oleifera leaves (15g/recipe)

干预措施: Dried Moringa oleifera leaves (Dietary Supplement)

Group B (Above 18)

Active Comparator

Dried Moringa oleifera leaves (15g/recipe)

干预措施: Dried Moringa oleifera leaves (Dietary Supplement)

结局指标

主要结局

Improvement in Hemoglobin status

时间窗: 3 months

Comparison of Hb levels pre and post intervention

次要结局

  • Changes in BMI(5 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Madeeha Munir

Former Lecturer Minhaj University

Kinnaird College for Women

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