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临床试验/NCT03003598
NCT03003598已完成不适用

The Effects of Endotracheal Intubation Via McGrath Videolaryngoscope on Intraocular Pressure

Inonu University0 个研究点目标入组 50 人开始时间: 2016年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
50
主要终点
Systolic blood pressure

研究概览

简要总结

In this study, the investigators aimed to compare the effects of endotracheal intubation via direct laryngoscope (DLS) and McGrath Videolaryngoscope (VL) on intraocular pressure.

详细描述

Total of 50 American Society of Anesthesiologist Grade 1-2, Mallampati score 1 or 2, age between 18 to 65 patient planned to undergo nonopthalmic surgery will be included to study. Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, American Society of Anesthesiologist Grade III and IV, Body mass index more than 35, difficult intubation, undergo obstetrical surgery and propofol, fentanyl, rocuronium contraindicated will be excluded from the study. Patients will be divided randomly into 2 groups as direct laryngoscopic and videolaryngoscopic intubation group. Patients will be preoxygenated with %100 O2 for 3 minutes then anesthesia will be induced using propofol 2 mg / kg, fentanyl 1 mcg/kg, and rocuronium 0,5 mg / kg in both groups. After 3 minutes mask ventilation, patients will be intubated (women with No:7-7,5, men with No:8-8,5 intubation tube) by oral route. systolic blood pressure, diastolic blood pressure, mean arterial pressure, peripheral oxygen saturation, perfusion indexwill be recorded and intraocular pressure measured by ophthalmologist by tonopen device will be recorded pre-induction (basal), after induction, 1,2,3,5 minutes after intubation, respectively. Period between handling of laryngoscope or videolaryngoscope after termination of mask ventilation and obtain end tidal carbon dioxide will be accepted as application time and recorded. Study will be terminated after 5th minute values taken.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASA (American Society of Anesthesiologist) Grade 1-2,
  • Mallampati score 1 or 2,
  • Age between 18 to 65,
  • Patient planned to undergo nonopthalmic surgery

排除标准

  • Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, ASA Grade III and IV, BMI more than 35,
  • Patients with difficult intubation,
  • Patients undergoing obstetrical surgery and propofol, fentanyl, rocuronium contraindicated

结局指标

主要结局

Systolic blood pressure

时间窗: From Beginning of Anesthesia induction to 5th minutes of intubation

Heart rate

时间窗: From Beginning of Anesthesia induction to 5th minutes of intubation

Intraocular pressure

时间窗: From Beginning of Anesthesia induction to 5th minutes of intubation

Adverse events

时间窗: within the first 24 hour after surgery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmet Selim Ozkan

M.D.

Inonu University

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