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临床试验/NCT03589638
NCT03589638已完成不适用

Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics; a Randomized, Double-blind Clinical Trial

Inonu University2 个研究点 分布在 1 个国家目标入组 3 人开始时间: 2018年6月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
3
试验地点
2
主要终点
intraocular pressure

研究概览

简要总结

In this study, participants aimed to compare the effects of direct laryngoscopic endotracheal intubation and videolaryngoscopic intubation with C-MAC videolaryngoscope and McGrath videolaryngoscope on intraocular pressure and hemodynamics.

详细描述

The maintenance of airway opened is one of the main responsibility of the anesthetist. Intubation procedure during anesthesia application benefits such as airway opening, airway and breathing control, aspiration hazard, respiratory effort and dead space reduction, surgical comfort and airway control during resuscitation. Laryngoscopy and tracheal intubation increases in heart rate, blood pressure and the intraocular pressure. The sympathetic-adrenal activity caused by the stimulation of the laryngeal and tracheal tissues is responsible for these negative effects. Endotracheal intubation with videolaryngoscopy is an alternative method used in airway management. Laryngoscopy and tracheal intubation under general anesthesia and laryngeal mask and airway control techniques cause different hemodynamic and catecholamine levels.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • American Society of Anesthesiologist Score 1-2
  • Mallampati 1 ve 2

排除标准

  • Glaucoma,
  • Diabetes mellitus
  • Cardiovascular and pulmonary disease
  • American Society of Anesthesiologist Score III-IV
  • Bdoy mass index greater than 35
  • Difficult intubation history
  • Obstetric surgery
  • Propofol, fentanyl, rocuronium contraindication

结局指标

主要结局

intraocular pressure

时间窗: From beginning of Anesthesia to 10th minute of surgery

The relevant values will be measured in the determined time.

次要结局

  • mean arterial pressure(From beginning of Anesthesia to 10th minute of surgery)
  • systolic arterial pressure(From beginning of Anesthesia to 10th minute of surgery)
  • diastolic arterial pressure(From beginning of Anesthesia to 10th minute of surgery)
  • heart rate(From beginning of Anesthesia to 10th minute of surgery)
  • peripheral oxygen saturation(From beginning of Anesthesia to 10th minute of surgery)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ahmet Selim Ozkan

Department of anesthesia

Inonu University

研究点 (2)

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