Phase I trial of S-1 with Lapatinb for metastatic breast cancer
- Conditions
- metastatic breast cancer
- Registration Number
- JPRN-UMIN000003583
- Lead Sponsor
- St. Luke's International Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 18
Not provided
1.with severe allergy to S-1 or Lapatinib 2.with active double cancer 3.infection,diarrhea,paralysis of intestine and intestinal obstruction which are judged to interfere with treatment,diabetes with incontrollable,and other sever complications 4.with mental disorder which become problem on clinical practice 5.with heart disease which become problem on clinical practice 6.with interstitial pneumonitis or with history of interstitial pneumonitis 7.with heart failure or with history of heart failure 8.with sever bone-marrow suppression, renal disorder,liver disorder 9.with large pleural effusion, or accumulation of ascitic fluid 10.with water diarrhea at the registration 11.treatment with flucytosine 12.pregnant,women who like be pregnant 13.doctor's decision not to be registered to this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method