in proposed study effect of nebulisation with magnesium sulphate , ketamine and lignocaine on heart rate and blood pressure during endotracheal intubation will be observed
Phase 3
- Conditions
- Health Condition 1: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systems
- Registration Number
- CTRI/2023/11/059926
- Lead Sponsor
- Department Of Anaesthesia And Intensive Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients in age group of 18-60 years
American Society of Anaesthesiologists (ASA) Status I and II
Patients undergoing elective surgery requiring general anaesthesia with endotracheal
intubation
Exclusion Criteria
Patients with difficult airway with Airway difficulty score >8
Morbid obesity BMI > 35 kg/m 2
Known airway pathology
Oropharyngeal surgeries
Surgery duration more than 3 hours
Patients at increased risk of aspiration like GERD, peptic ulcer
Previous upper gastrointestinal surgery
Known or anticipated difficult tracheal intubation or facemask ventilation
Coagulopathy or history of anticoagulant use
Cardiorespiratory or cerebrovascular disease
Cervical spine injury
12. Pregnant Patients
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparison of haemodynamic changes after nebulization with Ketamine, Magnesium <br/ ><br>Sulphate and lignocaine for endotracheal intubation in general anaesthesia.Timepoint: 1 , 2 ,3 , 5, 10 minutes
- Secondary Outcome Measures
Name Time Method To compare the effect of nebulization of ketamine, magnesium sulfate and lidocaine on <br/ ><br>postoperative sore throat in patients after endotracheal intubation.Timepoint: post operative sore throat grading