NSAIDs in Coronary Artery Disease Patients

Completed

• Conditions: CAD

• Registration Number: NCT01402804
• Lead Sponsor: Heinrich-Heine University, Duesseldorf

Brief Summary

Introduction:

Different groups already showed in retrospective subgroup analyses, that there is an increased risk for cardiovascular events in patients on a simultaneous ASA/NSAID treatment.

Methods:

Light-Transmission aggregometry

Hypothesis:

Simultaneous administration of different NSAIDs and ASA impair the platelet inhibiting effect of ASA.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-07
• Study First Submitted: 2011-07-25
• Study First Submitted QC: 2011-07-25
• Study First Posted: 2011-07-26
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Status Verified: 2013-11
• Last Update Submitted: 2013-11-08
• Last Update Posted: 2013-11-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• Patients on a simultaneous ASA, NSAID treatment
• > 18 years

Exclusion Criteria

• unconsciousness, not able to consent
• reanimation, cardiac shock

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Thromboxane-levels and light-transmission aggregometry in response to arachidonic acid	During hospital stay

Trial Locations

Locations (1)

Heinrich-Heine-University; 🇩🇪 Düsseldorf, NRW, Germany