NCT00832663已完成不适用
The Influence of Blocking Inflammatory Activity in Vivo on Skeletal Muscle Regeneration in Humans
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Muscle regeneration
研究概览
简要总结
The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration.
The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.
详细描述
The model employed to induce muscle damage is electrical stimulation. Muscle biopsies will be examined to follow the response of satellite cells and muscle regeneration. Study participants will be randomly assigned to a placebo or NSAID group in a double-blinded manner.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •does not exercise regularly
排除标准
- •displays contraindications for taking NSAID
- •well-trained
研究组 & 干预措施
NSAID
Experimental
receive NSAID
干预措施: NSAID (Drug)
Placebo
Placebo Comparator
receive placebo
干预措施: placebo (Drug)
结局指标
主要结局
Muscle regeneration
时间窗: 1 month
次要结局
- Muscle strength(1 month)
研究者
研究点 (1)
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