A Cross-sectional and Cohort Study of COVID-19 Patients With Post - Discharge Dysfunction

• Conditions: Cross-sectional Study; Respiratory Rehabilitation; Covid19; Cohort Study
• Interventions: Combination Product: Respiratory rehabilitation

• Registration Number: NCT04382534
• Lead Sponsor: Peking University Third Hospital

Brief Summary

Post-discharge rehabilitation regimens for covid-19 patients have not been supported by high-quality evidence-based medical evidence.The first part of this study is a cross-sectional study.The contents of the study were the factors related to the dysfunction of COVID - 19 patients after discharge from the hospital in Wuhan.The second part of this study is a cohort study.To observe the functional changes of COVID-19 patients after discharge in hospital rehabilitation, home rehabilitation and no rehabilitation, in order to propose a more safe and effective rehabilitation program.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-10
• Status Verified: 2020-04
• Study First Submitted: 2020-04-26
• Study First Submitted QC: 2020-05-07
• Last Update Submitted: 2020-05-07
• Study First Posted: 2020-05-11
• Last Update Posted: 2020-05-11
• Primary Completion: 2020-09-30
• Study Completion: 2020-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• patients with definite diagnosis of COVID-19 normal or severe
• patients who entered the isolation point <3 days after discharge
• 18-80 years old
• agree to join the queue

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Exclusion Criteria

• body temperature >38°C
• heart rate >120 times/min or <40 times/min, systolic blood pressure <90mmHg or >180mmHg, respiratory rate >25 times/min in calm state.Or above vital signs fluctuate significantly.
• continuous oxygen therapy is required.
• patients with myocarditis, pulmonary hypertension, congestive heart failure, fresh venous thromboembolic diseases, unstable fractures and other inappropriate exercise
• patients with consciousness disorders, severe sequelae of cerebral infarction, cognitive dysfunction, mental disorders, severe balance disorders, and severe bone and joint diseases, which affect evaluation and treatment
• other conditions that cannot be cooperated with rehabilitation treatment

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Systematic rehabilitation treatment	Respiratory rehabilitation	According to the systematic rehabilitation treatment program, the rehabilitation therapist entered the home for one-to-one rehabilitation treatment, once a day, for a total of 10 days.

Primary Outcome Measures

Name	Time	Method
The body function	Ten days	To take a MMT, 6-min walking test and Borg Index
ADL	Ten days	To take a modified Barthel index
Symptoms and signs	Ten days	To take a history and physical examination
Respiratory function	Ten days	To take a physical examination and mMRC

Trial Locations

Locations (1)

Huarunwugang general hospital; 🇨🇳 Wuhan, Hubei, China