Comparison of two anesthetic drugs in patients undergoing surgery for head injury
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/12/060707
- Lead Sponsor
- JIPMER Intramural Funding
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Emergency decompressive craniectomy for Traumatic Brain Injury
2. GCS <13
Exclusion Criteria
1. Polytrauma
2. Extradural hematoma
3. Known allergy to any of the study drugs
4. Pregnant patients
5. Hemodynamically unstable patients (Systolic Blood Pressure <90 mm Hg)
6. History of Uncontrolled Hypertension, Coronary Artery Disease, Psychiatric Disorder, renal or hepatic dysfunction
7. Refusal to Consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the intraoperative mean propofol consumptionTimepoint: End of Surgery
- Secondary Outcome Measures
Name Time Method To compare the hemodynamics, vasopressor requirement, <br/ ><br> opioid consumption between the three groups intraoperativelyTimepoint: Hemodynamics will be recorded at BASELINE & every 1 minute after induction until 5 minutes & then every 15 minutes.;To compare the subdural pressure, & brain relaxation, between the three groups intraoperativelyTimepoint: Intraoperative Period