Better pretreatment agent to reduce pain associated with propofol injection pain between ketamine vs lidocaine injection at the time of induction of general anaesthesia during surgical procedures
- Conditions
- Health Condition 1: K800- Calculus of gallbladder with acutecholecystitisHealth Condition 2: K566- Other and unspecified intestinal obstruction
- Registration Number
- CTRI/2023/09/057987
- Lead Sponsor
- Sms medical college jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients willing to participate in the study
2.Patients with age between 18 years to 55 years.
3.American Society of Anaesthesiologist (ASA) Grade I and II.
4.Undergoing elective urological, Gynaecological or general surgical procedures.
5.Patients undergoing routine elective surgical procedures under General anaesthesia
1.Patients not willing to participate in study
2.Patients with history of known hypersensitivity to Propofol injectable emulsion or any of its components.
3.Pregnant women.
4.Nursing mothers.
5.Morbid obesity (BMI >35).
6.Chronic steroid use.
7.Patients on antidepressants or opioid dependence or suffering from any psychiatric disease
8.Patients with chronic pain (arthritis, malignancies).
9.Those having difficulty in venous access
10.Uncontrolled hypertension
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence & severity of pain of propofol injection with a verbal response & behavioural signs such as facial grimacing,arm withdrawal or tears at different time intervals <br/ ><br>0 seconds <br/ ><br>1 minutes <br/ ><br>2 minutesTimepoint: 2 minutes
- Secondary Outcome Measures
Name Time Method Hemodynamic variables <br/ ><br>1 HR <br/ ><br>2 SBP <br/ ><br>3 DBP <br/ ><br>4 SpO2Timepoint: 20 minutes