Evaluate the efficacy of Vishwadi Guggulu in the management of Grudhrasi (Sciatica)

Phase 2/3

Not yet recruiting

• Conditions: Unspecified thoracic, thoracolumbar and lumbosacral intervertebral disc disorder. Ayurveda Condition: GRUDHRASI,

• Registration Number: CTRI/2025/05/086899
• Lead Sponsor: C S.M.S.S Ayurved Mahavidyalaya

Brief Summary

Grudhrasi is charaterized by Ruka, Toda, Spandana, Stambha, along Sphik, Prushta, Kati, Uru Jangha, Pada. Usually the symptoms develops gradually. When Kapha gets associated with Vata the patients experiences Tandra, Gaurava, Aruchi, beside the cardinal features of Grudhrasi. Clinically there is similarity in sign and symptoms of Grudhrasi and Sciatica Hence Grudhrasi can be correlated with Sciatica



The sciatic nerve is the longest and thickest nerve in the human body . It originates from the vertebral column at the level of 4th Lumbar to 3rd Sacral vertebrae and extend up to the feet hence the pain in the sciatica is felt in the lower back and radiates along the nerve up to the feet



In the Ayurveda Grudhrasi is considered as one of the most important Vata Vyadhi and patients facing lost of problems to manage this disease. Srotodusti lakshana and etiopathogenesis of Grudhrasi observe and explained so as to correct the srotodusti by Vishwadi Guggulu and its samprapti bhangatmak chikitsa



The Vishwadi Guggulu is advice in the Bharat Bhaisajya Ratnakar which is Vata and Kapha shamak. The management of patients at OPD level with cheap and effective remedies which should not hamper the daily routine of the patient. Therefore study is undertaken to evaluate the effect of Vishwadi Guggulu in the management of Grudhrasi

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-06
• Last Update Posted: 2025-05-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

1. Patients of Age group 30 to 60 years will be selected 2) Patients showing classical Lakshana of Grudhrasi (Sciatica) 3) Patients irrespective of genders will be selected.

Exclusion Criteria

1. osteoarthritis of spine, Spondylolithesis, Ankylosing spondylitis 2) Potts spine 3) Patient having age group less than 30 years and greater than 60 years 4) Pregnant women and Lactating mothers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Ruka (Pain)	28 days
Toda (Pricking sensation) Lakshanas will be decreased	28 days

Secondary Outcome Measures

Name	Time	Method
Stambha (Stiffness)	Spandana (Twitching)

Trial Locations

Locations (1)

C.S.M.S.S Ayurved Mahavidyalaya; 🇮🇳 Aurangabad, MAHARASHTRA, India

C.S.M.S.S Ayurved Mahavidyalaya

🇮🇳Aurangabad, MAHARASHTRA, India

Dr Sagar Genu Muthe

Principal investigator

8999114735

msagar8457@gmail.com