Does Deficiency in Vitamin D Induced Hypercoagulation or Thrombin Generation

Completed

• Conditions: Cardiovascular Disease
• Interventions: Drug: Vitamin D

• Registration Number: NCT01761669
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

Working hypothesis and aims: The aim of our study is to investigate whether vitamin D deficiency could cause increased thrombin generation and a hypercoagulable state healthy volunteers.

Methods:

In total 400 healthy volunteers are planned for inclusion in this trial. After signing an informed consent two blood samples will be obtained from each participant.

Expected results: invastigator expect to find that volunteers with vitamin D deficiency will have thrombin generation curve compatible with hypercoagulable state and returning to normal after treatment with vitamin D

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-12-04
• Study First Submitted QC: 2013-01-02
• Study First Posted: 2013-01-07
• Study Start: 2013-04
• Primary Completion: 2013-06
• Study Completion: 2013-07
• Status Verified: 2014-12
• Last Update Submitted: 2016-11-02
• Last Update Posted: 2016-11-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

age >18 healthy naive to drug treatment -

Exclusion Criteria

no exc criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
healthy voulnters	Vitamin D	-

Primary Outcome Measures

Name	Time	Method
the correlation between vitamin D levels and endogenous thrombin potential	3 month	one blood test

Trial Locations

Locations (1)

HaEmekMC; 🇮🇱 Afula, Israel