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临床试验/NCT04993807
NCT04993807
已完成
不适用

Data-driven Shared Decision-Making (SDM) to Reduce Symptom Burden in Atrial Fibrillation (AF)

Columbia University2 个研究点 分布在 1 个国家目标入组 75 人2024年3月25日

概览

阶段
不适用
干预措施
Shared decision-making tool
疾病 / 适应症
Atrial Fibrillation
发起方
Columbia University
入组人数
75
试验地点
2
主要终点
Decision satisfaction assessed using the Satisfaction with Decision Scale
状态
已完成
最后更新
2个月前

概览

简要总结

This study is a single-group feasibility study evaluating decision aid visualizations which display common post-ablation symptom patterns as a tool for shared decision-making. The specific aim of the clinical trial is to evaluate the feasibility of putting the visualizations into clinical practice (n=75). The hypothesis is that patients will report low decisional conflict and decision regret and high satisfaction with their decision about whether to undergo an ablation or not.

详细描述

Atrial fibrillation (AF) is the most common heart rhythm disorder, and nearly 90% of patients experience symptoms such as shortness of breath that directly impair their health-related quality of life (HRQoL). Catheter ablation is a minimally invasive, surgical procedure that is routinely performed to treat AF and associated symptoms with the goal of improving HRQOL, but also carries potentially serious risks. Shared decision-making (SDM), in which treatment decisions are aligned based on high quality evidence and patient values and goals of care, is a widely encouraged practice for navigating complex healthcare decisions such as these. However, SDM around rhythm and symptom management does not routinely occur due to a lack of detailed evidence about symptom improvement post-ablation, and a lack of decision aids to communicate evidence to patients. The overarching goal of this award is to create an interactive patient decision aid composed of established evidence from clinical trials together with novel "real world" evidence about symptom improvement post ablation mined from electronic health records (EHRs). The investigators propose to use "real-world evidence" drawn from electronic health records (EHRs) to characterize post-ablation symptom patterns, and display them in decision-aid visualizations to support shared decision-making (SDM). In this project, the investigators will first use natural language processing (NLP) and machine learning (ML) to extract and analyze symptom data from narrative notes in EHRs. The investigators will also employ a rigorous, user-centered design protocol created during the Principal Investigator's post-doctoral work to develop decision-aid visualizations. In the clinical trial, the investigators will evaluate the feasibility of implementing these interactive decision-aid visualizations in clinical practice.

注册库
clinicaltrials.gov
开始日期
2024年3月25日
结束日期
2025年8月20日
最后更新
2个月前
研究类型
Interventional
研究设计
Single Group
性别
All

研究者

责任方
Principal Investigator
主要研究者

Meghan Turchioe

Assistant Professor of Nursing

Columbia University

入排标准

入选标准

  • Diagnosis of paroxysmal AF according to International Classification of Diseases, Tenth Revision (ICD-10)
  • Scheduled consultation at NewYork-Presbyterian Hospital (NYP) to discuss catheter ablation
  • Symptomatic AF at baseline
  • Age 18 years and older
  • Able to read and speak English
  • Willing/able to provide informed consent

排除标准

  • Asymptomatic AF
  • Severe cognitive impairment
  • Major psychiatric illness
  • Concomitant terminal illness that would preclude participation

研究组 & 干预措施

Shared decision-making tool

Participants in this arm will view a shared decision-making tool while they are undergoing consultation to have an atrial fibrillation ablation.

干预措施: Shared decision-making tool

结局指标

主要结局

Decision satisfaction assessed using the Satisfaction with Decision Scale

时间窗: 12 weeks

Satisfaction about the decision to undergo atrial fibrillation will be assessed using the Satisfaction with Decision Scale on a scale of 1 (low satisfaction) to 5 (high satisfaction).

Decision regret assessed using the Decisional Regret Scale

时间窗: 12 weeks

Regret about the decision to undergo atrial fibrillation will be assessed using the Decision Regret Scale on a scale of 0 (no decision regret) to 100 (extremely high decision regret).

Decisional conflict assessed using the Decisional Conflict Scale

时间窗: Baseline

Conflict about the decision to undergo atrial fibrillation will be assessed using the Decisional Conflict Scale on a scale of 0 (no decisional conflict) to 100 (extremely high decisional conflict).

次要结局

  • Post-ablation symptom burden assessed using the Atrial Fibrillation severity Scale (AFSS)(12 weeks)
  • Post-ablation health-related quality of life assessed using the Atrial Fibrillation Effect on QualiTy-of-Life (AFEQT) questionnaire(12 weeks)

研究点 (2)

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