The effects of triacylglycerol structure of palmitic acid rich fats on postprandial changes in lipid and glucose metabolism

Completed

• Conditions: disturbances during the postprandial state; metabolic disturbances after a meal; 10013317

• Registration Number: NL-OMON33469
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 28

Inclusion Criteria

Body mass index (BMI) between 20-35 kg/m2
Age: 18-45 years
Serum total cholesterol < 7.8 mmol/L
Serum triacylglycerol < 3.0 mmol/L
Plasma glucose: < 7 mmol/L

Exclusion Criteria

-Smoking
-(Drug treatment against) Diabetes Mellitus
-Cardiovascular disease
-Familial hypercholesterolemia or lipid-lowering medication
-Diseases that can interfre with the outcome of the studies such as: COPD, asthma, epilepsy, IBD, reumatoid arthritis
-Unstable body weight (>3 kg weight gain or weight loss during the past 3 months)
-Abuse of drugs or alcohol (>28 consumptions a week)
-Participation in another trial or use of experimental products during the last months
-Having donated blood during the last two months
-Difficult or impossible to puncture during screening
-Not willing to consume animal-derived products

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Metabolic risk markers related to cardiovascular disease: Primary endpoints are<br /><br>postprandial lipemia and glycemia. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are changes in postprandial concentrations of insulin, and<br /><br>factors related to low-grade systemic inflammation and clotting activity, and<br /><br>of gut hormones. </p><br>