Prospective collection of blood plasma samples to identify potential biomarkers for prehospital stroke diagnostics

• Conditions: Patients with symptoms in whom stroke is considered as a differential diagnosis but in whom a different etiology emerges during the course (e.g., hypoglycemia, epileptic seizure with Todd's palsy); I63; I61; I62; Cerebral infarction; Intracerebral haemorrhage; Other nontraumatic intracranial haemorrhage

• Registration Number: DRKS00023063
• Lead Sponsor: Charité - Universitätsmedizin Berlin, Klinik für Neurologie, Campus Benjamin Franklin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-06
• Study Completion: 2022-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 151

Inclusion Criteria

legal capacity to consent or consent of legal guardian, written informed consent to participate in the study after oral and written information.

- Clinical suspicion of stroke

- Time window since onset of symptoms <4.5h

Exclusion Criteria

1. Patients who are unable to provide information and are not cared for, or whose legal caregiver cannot be reached in the further course.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pre-hospital differentiation between patients with an ischemic and hemorrhagic stroke without cerebral imaging using a biomarker or a combination of biomarkers

Secondary Outcome Measures

Name	Time	Method
Pre-hospital differentiation between patients with an ischemic or hemorrhagic stroke and patients with a stroke mimic without cerebral imaging using a biomarker or a combination of biomarkers