A screening protocol to collect a blood sample for the pharmacogenetic profiling of metabolic enzymes and drug transporters in male and female volunteers.
Completed
- Conditions
- pharmacogeneticsgenetic pharmacological research
- Registration Number
- NL-OMON49124
- Lead Sponsor
- QPS Netherlands B.V.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
1. Provision of written informed consent.
2. Male and female subjects aged >=18 years.
Exclusion Criteria
1. Previous participation in the current screening protocol.
2. The subject is, in the opinion of the Investigator, unlikely to comply with
the protocol or considered unsuitable for this study. For instance, when
drawing 20 mL of blood is exclusionary for a planned participation in a QPS
clinical trial.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Distribution of genotype of p-Gp, BCRP, OATP1B1, OATP1B, OAT1, OAT3, OCT1,<br /><br>OCT2, MATE1, 5-HTTLPR, CYP1A2, CYP2D6, CYP2C9, CYP2C19, CYP3A4. </p><br>
- Secondary Outcome Measures
Name Time Method <p>N.ap. </p><br>