The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

Early Phase 1

Terminated

• Conditions: Infertility
• Interventions: Dietary Supplement: dehydroepiandrosterone

• Registration Number: NCT01129830
• Lead Sponsor: Virginia Center for Reproductive Medicine

Brief Summary

This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.

Detailed Description

Ovarian reserve markers, such as FSH, estradiol, AMH, ovarian volume and antral follicle counts will be monitored on DHEA supplementation in a prospective fashion.

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2010-05-19
• Study First Submitted QC: 2010-05-24
• Study First Posted: 2010-05-25
• Status Verified: 2014-09
• Primary Completion: 2014-09
• Study Completion: 2014-09
• Last Update Submitted: 2014-09-18
• Last Update Posted: 2014-09-22

Recruitment & Eligibility

• Status: TERMINATED
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

• infertile women with diminished ovarian reserve

Exclusion Criteria

• women > 45

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Dehydroepiandrosterone	dehydroepiandrosterone	infertile women with low anti mullerian hormone levels

Primary Outcome Measures

Name	Time	Method
live birth rate	3 years	Live birth rate will be monitored for women who took DHEA supplementation

Secondary Outcome Measures

Name	Time	Method
number of oocytes	3 years	Number of retrieved oocytes for patients undergoing IVF will be monitored along with ovarian response

Trial Locations

Locations (1)

Virginia Center for Reproductive Medicine; 🇺🇸 Reston, Virginia, United States