The Analgesic Efficacy of Wound Infiltration With Tramadol
- Registration Number
- NCT02518438
- Lead Sponsor
- Yeditepe University Hospital
- Brief Summary
This double-blind, randomized trial examined whether tramadol wound infiltration decreased postoperative pain following cesarean delivery under general anesthesia or reduced the need for analgesics in the immediate postoperative period. Patients in the tramadol group consumed significantly less morphine at all time intervals than those in the control group. The investigators suggest that the use of wound infiltration with tramadol may be a useful technique in patients who undergo cesarean section under general anesthesia to reduce postoperative pain, improve recovery, and facilitate early contact of mothers with their babies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 60
- Nulliparity
- Gestation age between 37-40 weeks
- CS under general anesthesia
- Pre-eclampsia
- Cardiovascular problems
- Allergy to any of the study medications
- Chronic preoperative pain
- Regular analgesic use
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description the tramadol group Tramadol A preprepared 20 ml solution (tramadol 2 mgkg-1 within a 0.9% saline solution) was subcutaneously infiltrated after closure of the uterine incision and the rectus fascia.
- Primary Outcome Measures
Name Time Method The primary outcome measure in this study was cumulative morphine consumption. postoperative 24 hours The measure of need for analgesics in the immediate postoperative period in this study was cumulative morphine consumption.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Yeditepe University Hospital
🇹🇷Istanbul, Kozyatagı, Turkey