The study on a novel and easy way -vasoreactivity index- for assessment of both microvascular integrity and viable myocardium in coronary arteries using coronary pressure wire.
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0000013
- Lead Sponsor
- Pusan National University Yangsan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Terminated
- Sex
- All
- Target Recruitment
- 30
? In case of acute coronary syndrome, culprit lesion is documented in proximal or middle segment of major epicardial coronary arteries.
? reference vessel size is equal or greater than 3 mm in diameter so that stents used for this lesion are 3 mm or 3.5 mm in diameter.
? No history of previous myocardial infarction other than target vessel territory.
? Left main disease
? significant stenosis (defined by more than 50% of diameter stenosis) distal to taget lesion
? if there is relatively big branch vessel ( defined by more than 50% of diameter stenosis) with significant stenosis in target vessel.
? Left ventricle fraction < 30%
? severe left ventricle hypertrophy (>12mm) or hypertrophic cardiomyopathy
? creatinine > 2mg/dl
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Average transmural extent of infarction measured by cardiac MRI
- Secondary Outcome Measures
Name Time Method area of delayed hyperenhancement by cardiac MRI ;risk area measured by cardiac MRI ;serum myocardial enzyme (CK-MB, troponin I)