Effect of repetitive transcranial magnetic stimulation in children with generalised dystonia
- Conditions
- Health Condition 1: G249- Dystonia, unspecified
- Registration Number
- CTRI/2022/01/039806
- Lead Sponsor
- Child Neurology Division
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.Children with age between 5 to 18 years of either sex.
2.Presence of generalized dystonia
3.On stable antidystonic pharmacotherapy and physiotherapy for atleast 3 months
4. BFMDRS-M score of 52 or more
Primary Exclusion Criteria
1.Children diagnosed with progressive neurometabolic or neurodegenerative disorder on the basis of course of illness, neuroimaging and standard diagnostic evaluation.
2.Children with unilateral dystonia
3.Children with uncontrolled epilepsy defined as 4 or more seizures in last 6 months
4.Children with metallic implants anywhere in the body.
5.Children who underwent DBS/ pallidotomy.
6.Parents refusing consent for enrolment in the study.
Secondary Exclusion Criteria (to be applied at the end of observation phase I)
1.Change in antidystonia, antipsychotic or antiseizure medications during the observation period
2.Occurrence of seizure during the observation period
3.Repeat BFMDRS-M score after 4 week observation <52
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method