The efficacy of repeated transcranial magnetic stimulation on communication and skilled motor function of childre
- Conditions
- autism spectrum disorder
- Registration Number
- JPRN-UMIN000024216
- Lead Sponsor
- Osaka University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 20
Not provided
1. Those who suffer from physical comorbid disorders except developmental disorders. 2. Those who have any instrument including metal in the head except oral cavity. 3. Those who have a history of heart, gastrointestinal, chronic renal diseases, head trauma or brain tumors. 4. Those who were instrumented with a cardiac pacemaker, a deep brain or a spinal stimulation or drug-delivery pump. 5. Those who possess intracranial organic lesions and at increased risk for induction of convulsion. 6. Those who have a history of convulsive diseases including febrile seizures, epileptic seizures or epilepsy. 7. Those who take medicine that decrease the convulsive threshold such as anti-depressant, anti-psycotic or anti-histamine drugs. 8. Those who is judged to be not suitable for participating in the study by responsible or contributing doctors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Outcome for efficacy (evaluated on the day when rTMS is performed) a. coordinated upper limb movement evaluated by Trace Coder b. Motor evoked potential c. Sociocognitive function evaluated by GazeFinder 2. Outcome for safety a. the occurrence of adverse events and their extent
- Secondary Outcome Measures
Name Time Method 1. Outcome for efficacy (evaluated on the day when rTMS is performed) Global motor function evaluated by movement assessment battery for children 2 (M-ABC2) 2. Outcome for saftey The occurrence of severe adverse events at each site of stimulation