Cerebral Microembolism in the Critically Ill With Acute Kidney Injury
Not Applicable
Terminated
- Conditions
- Cerebral Embolism
- Registration Number
- NCT02621749
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Brief Summary
The primary objective of this study is to investigate the impact of continuous renal replacement therapy and intermittent renal replacement therapy on microbubble / cerebral microemboli generation in a cohort of critically ill patients with dialysis-dependent acute kidney injury.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
- > 18 yrs.
- Signed IC
Exclusion Criteria
- Heart disease (PFO, ASD, VSD, severe valvular disease)
- Atrial fibrillation
- Cerebrovascular pathology
- Missing temporal bone window
- Allergy to plastic contained in the investigative device (transcranial Doppler)
- Chronic kidney disease
- Pregnancy
- Participation in another study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Cerebral Microembolic Load detected by Transcranial Doppler Ultrasound During hemodialysis therapy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Bern
🇨🇭Bern, Switzerland
University Hospital Bern🇨🇭Bern, Switzerland